Denosumab

• Muscle, back, bone or joint pain
• Nausea or vomiting
• Constipation or diarrhea
• Slight tiredness
• Increased cholesterol levels

• Inform your doctor if any of the following occurs:
• Excessive muscle cramping
• Giddiness or confusion
• Excessive skin dryness, irritation or rashes
• Chest pain or shortness of breath
• Fever, pain upon urination, gum pain or gum bleeding
• Severe nausea or vomiting or abdominal pain
• Allergic reaction e.g. rash, swelling of eyelids and face

• Ensure you are taking enough calcium and vitamin D daily, unless otherwise instructed by your doctor.
• Maintain good oral hygiene. Inform your dentist that you are on Denosumab.
• For women: Use effective birth control and inform your doctor if you intend to get pregnant or breast-feed. 

Denosumab is an injection given under the skin (subcutaneously) at the upper arm, upper thigh or abdomen.

The interval between each injection you receive depends on what you are being treated for. Your doctor will inform you accordingly.

Do not shake the vial or syringe vigorously.

If you miss a dose, receive it as soon as possible by rescheduling an administration date with your clinic.