Axial Spondyloarthritis (Ankylosing Spondylitis)

Axial Spondyloarthritis (Ankylosing Spondylitis) - How to prevent?

Axial Spondyloarthritis (Ankylosing Spondylitis) - Causes and Risk Factors

Ankylosing spondylitis is hereditary. The major gene that causes this disease is HLA-B27. Almost 90% of people with ankylosing spondylitis are carriers of HLA-B27.

Other risk factors include history of skin psoriasis, uveitis, inflammatory bowel diseases, and reactive arthritis in the patient or his family members. Having the HLA-B27 does not mean that you will develop AS. Only 1-5% of HLA-B27-positive individuals in the general population develop AS.