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Assoc Prof Seow Wan Tew

MBBS, FRACS (Neurosurgery), FAMS (Neurosurgery)

Senior Consultant

National Neuroscience Institute

Specialty: Neurosurgery

Clinical Interest: Paediatric Neurosurgery

Conditions Treated by this Doctor:
Hydrocephalus, Paediatric Neurosurgery, Spasticity.

Clinical Appointments

Senior Consultant Department of Neurosurgery National Neuroscience Institute
Senior Consultant Department of Neurosurgery Singapore General Hospital
Senior Consultant Neurosurgical Service KK Women's and Children's Hospital

Profile

A/Prof Seow Wan Tew is Senior Consultant, Department of Neurosurgery at the National Neuroscience Institute (NNI), Singapore and formerly Head of Department of Neurosurgery. He is also a Senior Consultant Neurosurgeon at the KK Women’s and Children’s Hospital (KKH), Singapore and was formerly Head of the Neurosurgery Service at KKH.

A/Prof Seow is involved in the post-graduate training of neurosurgeons at the NNI and is a member of the Residency Advisory Committee for Neurosurgery Singapore and a member of the JCST Exit Examination Committee for Neurosurgery. He is Adjunct Associate Professor with the Duke-NUS Medical School.

He was the past Chair of the Education Committee for the International Society for Pediatric Neurosurgery and was actively involved in its educational programs. He is also on the teaching faculties of Pediatric Neurosurgery Courses in Asia, Europe, Latin America and Africa.

Education

MSurgEd, University of Melbourne, Australia, 2015
LLM, University of Melbourne, Australia, 2008
LLB (Hons), University of London, 2003
M Bus (IT) (RMIT University, Australia), 1998
FAMS (Neurosurgery), (Fellow, Academy of Medicine, Singapore), Specialist Neurosurgeon (Singapore Medical Council), 1994
FRACS (Neurosurgery), (Fellow, Royal Australasian College of Surgeons), 1991
MBBS (Singapore), 1982

Professional Appointments and Committee Memberships

Chief Medical Informatics Officer, National Neuroscience Institute
Member, Medical Board, National Neuroscience Institute
Chairman, Chapter of Neurosurgeons, Academy of Medicine, Singapore
Member, Residency Advisory Committee for Neurosurgery, Singapore
Member, JCST Exit Examination Committee for Neurosurgery, Singapore
Secretary, Asian Australasian Society of Neurological Surgeons (AASNS)
Education Committee and Past Chair, International Society for Paediatric Neurosurgery (ISPN)
By-Laws Chair, Asian-Australasian Society for Paediatric Neurosurgery (AASPN)
Adjunct Associate Professor, Duke-NUS Medical School

Awards

SingHealth Residency Outstanding Faculty Award Academic Year 2014/2015
Certificate of Outstanding Service, Royal Australasian College of Surgeons 2014
National Day Award 2013, Long Service Medal
National Neuroscience Institute, Long Service Award 2013
SingHealth Quality Service Award (SHQSA) (Star Award) (April 2011 – March 2012)
SHQSA (Gold Award) (April 2010 - March 2011)
SHQSA (Silver Award) (April 2009 - March 2010)
KKH Service From The Heart (SFTH) Award Jan-Jun 2012
KKH SFTH Award Jan-Jun 2011
KKH SFTH Award FY09 Q4
KKH SFTH Award FY08 Q4
NHG Service Champion Award Jun/Jul 2002

Research Interests

Publications

Chua FH, Thien A, Ng LP, Seow WT, Low DC, Chang KT, Lian DW, Loh E, Low SY. Post-operative diffusion weighted imaging as a predictor of posterior fossa syndrome permanence in paediatric medulloblastoma. Childs Nerv Syst. 2017 Feb 11. doi: 10.1007/s00381-017-3356-7
Foo AS, Khoo JC, Ong PL, Ho KH, Seow WT, Ng WH, Yeo TT. The Australasian contribution to the development of neurosurgery in Singapore. ANZ J Surg. 2016 Dec; 86(12):961-962. doi: 10.1111/ans.13743.
Lee L, Low S, Low D, Ng LP, Nolan C, Seow WT. Late pediatric ventriculoperitoneal shunt failures: a Singapore tertiary institution's experience. Neurosurg Focus. 2016 Nov;41(5):E7.
Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD Lipp ES, Perreault S, Cho YJ, Grant G, Kim SK, Lee JY, Rao AA, Giannini C, Li KK, Ng HK, Yao Y, Kumabe T, Tominaga T, Grajkowska WA, Perek-Polnik M, Low DC, Seow WT, Chang KT, Mora J, Pollack IF, Hamilton RL, Leary S, Moore AS, Ingram WJ, Hallahan AR, Jouvet A, Fèvre-Montange M, Vasiljevic A, Faure-Conter C, Shofuda T, Kagawa N, Hashimoto N, Jabado N, Weil AG, Gayden T, Wataya T, Shalaby T, Grotzer M, Zitterbart K, Sterba J, Kren L, Hortobágyi T, Klekner A, László B, Pócza T, Hauser P, Schüller U, Jung S, Jang WY, French PJ, Kros JM, van Veelen ML, Massimi L, Leonard JR, Rubin JB, Vibhakar R, Chambless LB, Cooper MK, Thompson RC, Faria CC, Carvalho A, Nunes S, Pimentel J, Fan X, Muraszko KM, López-Aguilar E, Lyden D, Garzia L, Shih DJ, Kijima N, Schneider C, Adamski J, Northcott PA, Kool M, Jones DT, Chan JA, Nikolic A, Garre ML, Van Meir EG, Osuka S, Olson JJ, Jahangiri A, Castro BA, Gupta N, Weiss WA, Moxon-Emre I, Mabbott DJ, Lassaletta A, Hawkins CE, Tabori U, Drake J, Kulkarni A, Dirks P, Rutka JT, Korshunov A, Pfister SM, Packer RJ, Ramaswamy V, Taylor MD. Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis. Lancet Oncol. 2016 Apr;17(4):484-95.
Foo As, Koo JC, Ong PL, Ho KH, Seow WT, Yeo TT. A Tribute to Tham Cheok Fai, “Founding Father” of Singapore Neurosurgery. Ann Acad Med Singapore. 2015;44(8): 307-11.
Yeo JJ, Low SY, Seow WT, Low DC. Pediatric de novo cerebral AVM: report of two cases and review of literature. Childs Nerv Syst. 2015; 31(4): 609-14.
Low SYY, Seow WT. The Child with a Brain Tumor: Vulnerability Perspectives from Neurosurgery. Asian Bioethics Review. 2015; 7(2): 250-256.
Teo WY, Ross J, Bollo R, Seow WT, Tan AM, Kang SG, MD, Kim DS, Li XN, Lau CC, Mohila CA, Adesina AM, Su JMF. Atypical location and clinical behavior of a subset of intracranial germ cell tumors in children younger than 3 years of age. J Neurosurg Pediatr. 2014 Oct; 14(4):348-55.
Lim E, Rai E, Seow WT. Feasibility of anaesthetic provision for paediatric patients undergoing off-site intraoperative MRI-guided neurosurgery: the Singapore experience from 2009 to 2012. Anaesth Intensive Care. 2013 Jul;41(4):535-42.
Ling JM, Tiruchelvarayan, Seow WT, Ng HB. Surgical treatment of adult and pediatric C1/C2 subluxation with intraoperative computed tomography guidance. Surg Neurol Int 2013; 4: S109-17.
A Teo, Gan BK, Tung JS, Low Y, Seow WT. Low-lying spinal cord and tethered cord syndrome in children with anorectal malformations. Singapore Med J. 2012 Sep;53(9):570-6.
Loke P, Seow WT. Mediation in Medical Disputes. Asian Journal on Mediation 2012.
Fung W, Hasan MY, Loh AH, Chua JH, Yong MH, Knight L, Hwang WS, Chan MY, Seow WT, Jacobsen AS, Chui CH. Gene expression of TRK neurotrophin receptors in advanced neuroblastomas in Singapore - a pilot study. Pediatr Hematol Oncol. 2011 Oct;28(7):571-8.
Ng YPV, Gan BK, Seow WT. Screening and Management of Tethered Spinal Cord in Children. JPOG May/Jun 2010: 105- 114.
Low D, Seow WT, Ng WH, Drake J. Management of Ventriculo-Peritoneal Shunts in the Paediatric Population. Asian J Neurosurg, 2010 Jan; 5 (1) 7-14.
Yong MH, Hwang WS, Knight LA, Fung W, Chan MY, Seow WT, Chui CH. Comparing histopathological classification with MYCN, 1p36 and 17q status detected by fluorescence in situ hybridisation from 14 untreated primary neuroblastomas in Singapore. Singapore Med J. 2009 Nov; 50(11):1090-4.
Loh APH, Ha C, Chua JHY, MBBS, Seow WT, Chan MY, Tan AM, Chui CH. Delays in Diagnosis of Pediatric Solid Tumors in Singapore. J Pediatr Hematol Oncol. 2009 Oct;31(10):734-8.
Ng WH, Gan BK, Seow WT. Images in Neuroscience: Question. A teenage girl with thoracic myelopathy. J Clin Neurosci. 2009 Jan; 16: 283.
Ng WH, Gan BK, Seow WT. Images in Neuroscience: Answer. A teenage girl with thoracic myelopathy. J Clin Neurosci. 2009 Jan; 16: 353.
Tan RM, Chng SM, Seow WT, Wong J, Lim CC. 'Moya' than meets the eye: neurofibromatosis type 1 associated with Moyamoya syndrome. Singapore Med J. 2008 Apr;49(4):e107-9.
Thorat JD, Wang EC, Lee KK, Seow WT, Ng I. Barbiturate therapy for patients with refractory intracranial hypertension following severe traumatic brain injury: Its effects on tissue oxygenation, brain temperature and autoregulation. J Clin Neurosci. 2008 Feb;15(2):143-8
Chan MY, Teo WY, Seow WT, Tan AM. Epidemiology, management and treatment outcome of medulloblastoma in Singapore. Ann Acad Med Singapore. 2007 May; 36(5):314-8.
Chawla A, Emmanuel JV, Seow WT, Lou J, Teo HE, Lim CC. Paediatric PNET: pre-surgical MRI features. Clin Radiol. 2007 Jan;62(1):43-52.
Wong CH, Foo CL, Seow WT. Calcified cephalohematoma: classification, indications for surgery and techniques. J Craniofac Surg. 2006 Sep;17(5):970-9.
Lee KK, Seow WT, Ng I. Demographical profiles of adult severe traumatic brain injury patients: implications for healthcare planning. Singapore Med J. 2006 Jan;47(1):31-6.
Yuen HW, Gan BK, Seow WT, Tan HK. Dural sinus thrombosis after minor head injury in a child. Ann Acad Med Singapore. 2005 Nov;34(10):639-3.
Wong JPL, Seow WT, Yeo GSH. Characteristics of Six Newborn Infants with Postnatal Findings of Severe Intracranial Haemorrhage. Ann Acad Med Singapore 2004;33:789-92
Ng WH, Yeo TT, Seow WT. Spontaneous Epidural Hemorrhage- Report of 2 cases. J Clin Neurosci. 2004 Sep;11(7):791-4.
Chng SM, Lim CC, Seow WT. Intracerebral schwannoma--a rare cause of epilepsy. Ann Acad Med Singapore. 2003 Jul;32(4):547-9.
Ng WH, Seow WT. Tethered cord syndrome preceding syrinx formation--serial radiological documentation. Childs Nerv Syst. 2001 Aug;17(8):494-6.
Tung MY, Ong PL, Seow WT, Tan KK. A study on the efficacy of intraventricular urokinase in the treatment of intraventricular haemorrhage. Br J Neurosurg. 1998 Jun;12(3):234-9.
Low Y, Foo CL, Seow WT. Childhood temporal bone osteoblastoma: a case report. J Pediatr Surg. 2000 Jul;35(7):1127-9.
Wong SH, Yeo TT, Seow WT, Tan KK, Ong PL. Spontaneous subarachnoid haemorrhage and outcome--results from Tan Tock Seng Hospital, Singapore. Singapore Med J. 1999 Jul;40(7):459-64.
Ng I, Lew TW, Yeo TT, Seow WT, Tan KK, Ong PL, San WM. Outcome of patients with traumatic brain injury managed on a standardised head injury protocol. Ann Acad Med Singapore. 1998 May;27(3):332-9.
Chua JJ, Tan PK, Seow WT. Leptomeningeal metastasis with urological presentation. Singapore Med J. 1997 Jun;38(6):266-7.
Ng PY, Seow WT. Brain abscesses: review of 30 cases treated with surgery. Aust N Z J Surg. 1995 Sep;65(9):664-6.
Seow WT, Balaji S. Surgery for brain metastases in Singapore. Singapore Med J. 1992 Aug;33(4):352-4.
Seow WT, Yeo TT, Ong PL. Tuberculoma of the brain--report of 2 cases and review of literature. Singapore Med J. 1991 Dec;32(6):427-30.
Yeo TT, Seow WT, Lee KH, Tan KK, Ong PL. CT-directed BRW stereotactic neurosurgery: local experience with 42 cases. Singapore Med J. 1991 Oct;32(5):307-11.

Books & Chapters

WT Seow. Common Neurosurgical Problems in The Baby Bear Book, A Practical Guide on Paediatrics – 2008. KK Women’s & Children’s Hospital.
WT Seow and GSH Yeo. Antenatal Screening and Management in Cerebrospinal Fluid Disorders, C Mallucci and S Sgouros (Eds), December 2009. Informa Medical Books.
CK Lee & WT Seow. Developmental Anomalies of the Central Nervous System in Essential Practice of Neurosurgery, KKN Kalangu, Y Kato and G Dechambenott (Eds), 2009. Access Publishing, Japan.
Low SYY, Tan MTL, Seow WT. Primary Intracranial Germ Cell Tumors in Current Progress in Neurosurgery Volume 2. BK Misra, E Laws and AH Kaye (Eds).

Abstracts

Tumors of the central nervous system in the Republic of Singapore. Das A, Yeo TT, Seow WT, Ong PL, Yap WM. Neurology 1999:52(6);A196-A196.
Combined central diabetes insipidus and cerebral salt wasting after craniotomy. Loh TF, Lee WRW. Goh YCK, Seow WT Critical Care, 2000;4 (Suppl 1):178.
Brain cancer in children - A surgical review of malignant brain tumours from a paediatric hospital. Seow WT, Tang KK. Med J Malaysia, 2004;58: 82.
Cranial Reduction for Macrocrania from Neglected Hydrocephalus. Seow WT, Foo CL. Med J Malaysia, 2004;58:161.
Complex fronto-ethmoidal encephaloceles and their outcomes. Seow WT, Gan BK. Childs Nerv Syst Aug 2005; 21: 841.
Calcified Cephalohematoma: Classification, Indications for Surgery and Techniques. Wong CH, Foo CL, Seow WT. Childs Nerv Syst Aug 2006; 22(8): 1031.
Near Drowning in Children – Is there a role for intensive neurosurgical monitoring? Seow WT, Gan BK, Chan YH. Childs Nerv Syst Aug 2007;23: 1065.
Improving healthcare for paediatric neurosurgical patients using a rights-based approach. Seow WT. Childs Nerv Syst Aug 2007;23: 1084.
Prognostic significance of metastases at diagnosis on survival outcome of childhood medulloblastoma in Singapore. Teo WY, Seow WT, Chan MY, Tan AM. Pediatric Blood & Cancer 2007;49(4): 493-494.
Endocrinopathies in Children with Fronto-ethmoidal Encephaloceles. Seow WT, Gan BK. Childs Nerv Syst 2008; 24:1274.
Childhood intracranial germ cell tumors: Experience in a multiracial Asian population over 18 years. Teo WY, Tan AM, Chan MY, Sethi V, Seow WT. Neuro Oncol 2008;10(3): 417-418.
A preliminary evaluation of the utility of soluble c-kit (s-kit) as a cerebrospinal fluid (CSF) marker for intracranial germinomas. Seow WT, Fung WKY, Koh XY, Hwang LA, Chang LK Childs Nerv Syst 2011;27: 1788.
1st-year-shunt-failure rate as a clinical quality indicator in neurosurgical practice — an institutional experience. Seow WT. Childs Nerv Syst 2012;28: 766.
Atypical teratoid rhabdoid tumor - report from a children's cancer centre in Singapore. Soh SY, Chan MY, Seow WT, Chang K, Ng WH, Tan AM. Neuro Oncol 2012; 14 (supp1): i3-4.