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Assoc Prof Liao Ping

Assoc Prof Liao Ping

M.B.B.S., Ph.D

Head & Principal Investigator, Calcium Signalling Laboratory

Research (National Neuroscience Institute)

National Neuroscience Institute

Research Interest:

Ion channels in central nervous system diseases including stroke, head injury, vascular dementia etc.

Research Appointments

Head & Principal Investigator, Calcium Signalling Laboratory Research (National Neuroscience Institute) Research (National Neuroscience Institute)

Profile

A/Prof Liao Ping is Head & Principal Investigator of the Calcium Signalling Laboratory, NNI.

Professional Appointments and Committee Memberships

Clinician Scientist, National Neuroscience Institute
Head & Principal Investigator, Calcium Signalling Laboratory, National Neuroscience Institute, Research
Joint Assistant Professor, Singapore Institute of Technology
Joint Assistant Professor without tenure (Track IIA-research), Duke-NUS Medical School
Chairperson and Senior Management Representative, NNI Biosafety Committee, 2017 - Present
Chairperson, Institutional Animal Care and Use Committees (IACUC), NNI (TTSH Campus), 2017 - Present
Co-Director, NNI-TTSH Animal Research Facility, Nov 2017 - Present
Management Representative, SingHealth Institutional Biosafety Committee (SingHealth IBC), Jan 2018 - Present

Education

M.B.B.S., M. Surgery (Neurosurgery), West China University of Medical Sciences (Sichuan, P.R. China), 1989 - 1996
Ph.D. Division of Neurosurgery, Department of Surgery, National University of Singapore, 1997 - 2002

Awards

PhD Scholarship, National University of Singapore, 1997 - 2001
Swee-Liew Wadsworth Research Gold Award, 2014

Research Studies

Publications

Low SW, Gao Y, Wei S, Chen B, Nilius B, Liao P. Development and characterization of a monoclonal antibody blocking human TRPM4 channel. Sci Rep. 2021 May 17;11(1):10411.
Wei S, Low SW, Poore CP, Chen B, Gao Y, Nilius B, Liao P. Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia. Front Cell Dev Biol. 2020 Oct 19;8:562584.
Hazalin NAMN, Liao P, Hassan Z. TRPM4 inhibition improves spatial memory impairment and hippocampal long-term potentiation deficit in chronic cerebral hypoperfused rats. Behav Brain Res. 2020 Sep 1;393:112781.
Chen B, Gao Y, Wei S, Low SW, Ng G, Yu D, Tu TM, Soong TW, Nilius B, Liao P. TRPM4-specific blocking antibody attenuates reperfusion injury in a rat model of stroke. Pflugers Arch. 2019 Dec;471(11-12):1455-1466.
Zhang E, Liao P. Brain-derived neurotrophic factor and post-stroke depression. J Neurosci Res. 2020 Mar;98(3):537-548.
Gao Y, Liao P. TRPM4 channel and cancer. Cancer Lett. 2019 Jul 10;454:66-69.
Loh KY, Wang Z, Liao P. Oncotic Cell Death in Stroke. Rev Physiol Biochem Pharmacol. 2019;176:37-64.
Chen B, Ng G, Gao Y, Low SW, Sandanaraj E, Ramasamy B, Sekar S, Bhakoo K, Soong TW, Nilius B, Tang C, Robins EG, Goggi J, Liao P. Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury. Transl Stroke Res. 2019 Feb; 10(1):91-103.
Hu Z, Li G, Wang JW, Chong SY, Yu D, Wang X, Soon JL, Liang MC, Wong YP, Huang N, Colecraft HM, Liao P, Soong TW. Regulation of Blood Pressure by Targeting CaV1.2-Galectin-1 Protein Interaction. Circulation. 2018 Oct 2;138(14):1431-1445.